Interfacial Activity of Phosphonated-PEG Functionalized Cerium Oxide Nanoparticles

Redispersible hybrid nanopowders: cerium oxide nanoparticle complexes with phosphonated-PEG oligomers.

Rare earth cerium oxide (ceria) nanoparticles are stabilized using end-functional phosphonated-PEG oligomers. The complexation process and structure of the resulting hybrid core-shell singlet nanocolloids are described, characterized, and modeled using light and neutron scattering data. The adsorption mechanism is nonstoichiometric, yielding the number of adsorbed chains per particle N(ads) = 2...

Nanoparticles of Cerium Oxide Having Superoxide Dismutase Activity

Oxidase-like activity of polymer-coated cerium oxide nanoparticles.

Inorganic enzyme? Ceria nanoparticles exhibit unique oxidase-like activity at acidic pH values. These redox catalysts can be used in immunoassays (ELISA) when modified with targeting ligands (see picture; light blue and yellow structures are nanoparticles with attached ligands). This modification allows both for binding and for detection by the catalytic oxidation of sensitive colorimetric dyes...

Cerium oxide nanoparticles in cancer

With the development of many nanomedicines designed for tumor therapy, the diverse abilities of cerium oxide nanoparticles (CONPs) have encouraged researchers to pursue CONPs as a therapeutic agent to treat cancer. Research data have shown CONPs to be toxic to cancer cells, to inhibit invasion, and to sensitize cancer cells to radiation therapy and chemotherapy. CONPs also display minimal toxic...

Cytotoxicity and antibacterial activity of gold-supported cerium oxide nanoparticles

BACKGROUND Cerium oxide nanoparticles (CeO2) have been shown to be a novel therapeutic in many biomedical applications. Gold (Au) nanoparticles have also attracted widespread interest due to their chemical stability and unique optical properties. Thus, decorating Au on CeO2 nanoparticles would have potential for exploitation in the biomedical field. METHODS In the present work, CeO2 nanoparti...